Altered metabolism in cancer

Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in BMC Systems Biology by Va...

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Detalles Bibliográficos
Autores principales: Locasale, Jason W, Cantley, Lewis C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892450/
https://www.ncbi.nlm.nih.gov/pubmed/20598111
http://dx.doi.org/10.1186/1741-7007-8-88
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author Locasale, Jason W
Cantley, Lewis C
author_facet Locasale, Jason W
Cantley, Lewis C
author_sort Locasale, Jason W
collection PubMed
description Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in BMC Systems Biology by Vasquez et al. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs. See research article: http://www.biomedcentral.com/1752-0509/4/58/
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spelling pubmed-28924502010-06-26 Altered metabolism in cancer Locasale, Jason W Cantley, Lewis C BMC Biol Commentary Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in BMC Systems Biology by Vasquez et al. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs. See research article: http://www.biomedcentral.com/1752-0509/4/58/ BioMed Central 2010-06-25 /pmc/articles/PMC2892450/ /pubmed/20598111 http://dx.doi.org/10.1186/1741-7007-8-88 Text en Copyright ©2010 Locasale and Cantley; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Locasale, Jason W
Cantley, Lewis C
Altered metabolism in cancer
title Altered metabolism in cancer
title_full Altered metabolism in cancer
title_fullStr Altered metabolism in cancer
title_full_unstemmed Altered metabolism in cancer
title_short Altered metabolism in cancer
title_sort altered metabolism in cancer
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892450/
https://www.ncbi.nlm.nih.gov/pubmed/20598111
http://dx.doi.org/10.1186/1741-7007-8-88
work_keys_str_mv AT locasalejasonw alteredmetabolismincancer
AT cantleylewisc alteredmetabolismincancer

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