A Major Histocompatibility Class I Locus Contributes to Multiple Sclerosis Susceptibility Independently from HLA-DRB1*15:01

BACKGROUND: In Northern European descended populations, genetic susceptibility for multiple sclerosis (MS) is associated with alleles of the human leukocyte antigen (HLA) Class II gene DRB1. Whether other major histocompatibility complex (MHC) genes contribute to MS susceptibility is controversial....

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Detalles Bibliográficos
Autores principales: Cree, Bruce A. C., Rioux, John D., McCauley, Jacob L., Gourraud, Pierre-Antoine F. D., Goyette, Philippe, McElroy, Joseph, De Jager, Philip, Santaniello, Adam, Vyse, Timothy J., Gregersen, Peter K., Mirel, Daniel, Hafler, David A., Haines, Jonathan L., Pericak-Vance, Margaret A., Compston, Alastair, Sawcer, Stephen J., Oksenberg, Jorge R., Hauser, Stephen L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892470/
https://www.ncbi.nlm.nih.gov/pubmed/20593013
http://dx.doi.org/10.1371/journal.pone.0011296

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