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Bioinformatic analysis of the human DHRS4 gene cluster and a proposed mechanism for its transcriptional regulation

BACKGROUND: The human DHRS4 gene cluster consists of three genes, DHRS4, DHRS4L2 and DHRS4L1. Among them, DHRS4 encodes NADP(H)-dependent retinol dehydrogenase/reductase. In a previous study, we investigated the alternative splicing of DHRS4 and DHRS4L2. DHRS4L1 was added to the gene cluster recentl...

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Detalles Bibliográficos
Autores principales: Su, Zhong-Jing, Zhang, Qiao-Xia, Liu, Ge-Fei, Song, Xu-Hong, Li, Qi, Wang, Rui-Jian, Chen, Hai-Bin, Xu, Xiao-Yuan, Sui, Xu-Xia, Huang, Dong-Yang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892492/
https://www.ncbi.nlm.nih.gov/pubmed/20525226
http://dx.doi.org/10.1186/1471-2199-11-43