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Immune disease expressed in liver and platelets in an adolescent: a case report

We report a case of a 15-year-old boy with autoimmune hepatitis lacking common serologic markers and normal gammaglobulinemia associated with immune thrombocytopenia and family history of psoriasis. He presented to our department with a 4-year history of a cervical posterior lymphadenopathy and rece...

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Detalles Bibliográficos
Autores principales: Antunes, Henedina, Rocha, Ruben, Silva, Nicole, Pontes, Teresa, Antunes, Ana, Martins, Sofia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892502/
https://www.ncbi.nlm.nih.gov/pubmed/20540743
http://dx.doi.org/10.1186/1824-7288-36-42
Descripción
Sumario:We report a case of a 15-year-old boy with autoimmune hepatitis lacking common serologic markers and normal gammaglobulinemia associated with immune thrombocytopenia and family history of psoriasis. He presented to our department with a 4-year history of a cervical posterior lymphadenopathy and recent petechiae. Previous laboratory results 6 months before already showed hepatocellular injury. After exclusion of other causes, the diagnosis of autoimmune hepatitis was made based on clinical grounds, associated immune disorder and histological features of liver biopsy. The authors alert for this atypical presentation of autoimmune hepatitis and associated immune thrombocytopenia.