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Clinical, Biological and Genetic Analysis of Prepubertal Isolated Ovarian Cyst in 11 Girls
BACKGROUND: The cause of isolated gonadotropin-independent precocious puberty (PP) with an ovarian cyst is unknown in the majority of cases. Here, we describe 11 new cases of peripheral PP and, based on phenotypes observed in mouse models, we tested the hypothesis that mutations in the GNAS1, NR5A1,...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892512/ https://www.ncbi.nlm.nih.gov/pubmed/20593028 http://dx.doi.org/10.1371/journal.pone.0011282 |