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Sclerosing Variant of the Bronchioloalveolar Carcinoma: Imaging Findings in an Atypical Case

Bronchioloalveolar carcinoma remains one of the most enigmatic lung cancers, demonstrating varied growth patterns, mixed histological features, and confusing clinical manifestations. This paper reports a case of an unusual form of presentation: a sclerosing type associated with desmoplastic reaction...

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Detalles Bibliográficos
Autores principales: Constantino, Carolina Lamas, Marchiori, Edson, Zanetti, Gláucia, Muccillo, Antonio, Pereira, Mariana Leite, Abdalla, Guilherme, Martins, Pedro, Ventura, Nina, Canellas, Rodrigo, Brandão, Viviane, Varella de Oliveira, Romulo
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892667/
https://www.ncbi.nlm.nih.gov/pubmed/20589217
http://dx.doi.org/10.1155/2010/361265
Descripción
Sumario:Bronchioloalveolar carcinoma remains one of the most enigmatic lung cancers, demonstrating varied growth patterns, mixed histological features, and confusing clinical manifestations. This paper reports a case of an unusual form of presentation: a sclerosing type associated with desmoplastic reaction and cicatrization. A 75-year-old woman was admitted with persistent dry cough and progressive dyspnea. Physical examination showed bilateral inspiratory crackles. A chest radiograph and high-resolution computed tomography demonstrated confluent airspace nodules, forming areas of consolidation in both lungs, with signs of architectural distortion. The lung biopsy revealed a nonmucinous sclerosing bronchioloalveolar carcinoma.