Subcapsular Sinus Macrophages Prevent CNS Invasion Upon Peripheral Infection With a Neurotropic Virus

Lymph nodes (LNs) capture microorganisms that breach the body’s external barriers and enter draining lymphatics, limiting the systemic spread of pathogens1. Recent work has shown that CD11b(+)CD169(+) macrophages, which populate the subcapsular sinus (SCS) of LNs, are critical for clearance of virus...

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Detalles Bibliográficos
Autores principales: Iannacone, Matteo, Moseman, E. Ashley, Tonti, Elena, Bosurgi, Lidia, Junt, Tobias, Henrickson, Sarah E., Whelan, Sean P., Guidotti, Luca G., von Andrian, Ulrich H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892812/
https://www.ncbi.nlm.nih.gov/pubmed/20577213
http://dx.doi.org/10.1038/nature09118

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