Inside-Out Regulation of ICAM-1 Dynamics in TNF-α-Activated Endothelium

BACKGROUND: During transendothelial migration, leukocytes use adhesion molecules, such as ICAM-1, to adhere to the endothelium. ICAM-1 is a dynamic molecule that is localized in the apical membrane of the endothelium and clusters upon binding to leukocytes. However, not much is known about the regul...

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Detalles Bibliográficos
Autores principales: van Buul, Jaap D., van Rijssel, Jos, van Alphen, Floris P. J., Hoogenboezem, Mark, Tol, Simon, Hoeben, Kees A., van Marle, Jan, Mul, Erik P. J., Hordijk, Peter L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893160/
https://www.ncbi.nlm.nih.gov/pubmed/20596527
http://dx.doi.org/10.1371/journal.pone.0011336

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