CXCR2 Signaling Protects Oligodendrocytes and Restricts Demyelination in a Mouse Model of Viral-Induced Demyelination

BACKGROUND: The functional role of ELR-positive CXC chemokines during viral – induced demyelination was assessed. Inoculation of the neuroattenuated JHM strain of mouse hepatitis virus (JHMV) into the CNS of susceptible mice results in an acute encephalomyelitis that evolves into a chronic demyelina...

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Detalles Bibliográficos
Autores principales: Hosking, Martin P., Tirotta, Emanuele, Ransohoff, Richard M., Lane, Thomas E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893165/
https://www.ncbi.nlm.nih.gov/pubmed/20596532
http://dx.doi.org/10.1371/journal.pone.0011340

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