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Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack
In humans, absence of Fragile X mental retardation protein (FMRP), an RNA-binding protein, results in Fragile X syndrome (FXS), the most common inherited form of intellectual disability. Here we report through biochemical and electrophysiological studies that FMRP binds the C-terminus of the Slack s...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893252/ https://www.ncbi.nlm.nih.gov/pubmed/20512134 http://dx.doi.org/10.1038/nn.2563 |