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Visualization of Tumor Angiogenesis Using MR Imaging Contrast Agent Gd-DTPA-anti-VEGF Receptor 2 Antibody Conjugate in a Mouse Tumor Model
OBJECTIVE: To visualize tumor angiogenesis using the MRI contrast agent, Gd-DTPA-anti-VEGF receptor 2 antibody conjugate, with a 4.7-Tesla MRI instrument in a mouse model. MATERIALS AND METHODS: We designed a tumor angiogenesis-targeting T1 contrast agent that was prepared by the bioconjugation of g...
Autores principales: | Jun, Hong Young, Yin, Hong-Hua, Kim, Sun-Hee, Park, Seong Hoon, Kim, Hun Soo, Yoon, Kwon-Ha |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Radiology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893316/ https://www.ncbi.nlm.nih.gov/pubmed/20592929 http://dx.doi.org/10.3348/kjr.2010.11.4.449 |
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