CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy

We have studied the photodynamic properties of novel CdTe quantum dots—methylene blue hybrid photosensitizer. Absorption spectroscopy, photoluminescence spectroscopy, and fluorescence lifetime imaging of this system reveal efficient charge transfer between nanocrystals and the methylene blue dye. Ne...

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Detalles Bibliográficos
Autores principales: Rakovich, Aliaksandra, Savateeva, Diana, Rakovich, Tatsiana, Donegan, John F, Rakovich, Yury P, Kelly, Vincent, Lesnyak, Vladimir, Eychmüller, Alexander
Formato: Texto
Lenguaje:English
Publicado: Springer 2010
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893770/
https://www.ncbi.nlm.nih.gov/pubmed/20671788
http://dx.doi.org/10.1007/s11671-010-9553-x
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author Rakovich, Aliaksandra
Savateeva, Diana
Rakovich, Tatsiana
Donegan, John F
Rakovich, Yury P
Kelly, Vincent
Lesnyak, Vladimir
Eychmüller, Alexander
author_facet Rakovich, Aliaksandra
Savateeva, Diana
Rakovich, Tatsiana
Donegan, John F
Rakovich, Yury P
Kelly, Vincent
Lesnyak, Vladimir
Eychmüller, Alexander
author_sort Rakovich, Aliaksandra
collection PubMed
description We have studied the photodynamic properties of novel CdTe quantum dots—methylene blue hybrid photosensitizer. Absorption spectroscopy, photoluminescence spectroscopy, and fluorescence lifetime imaging of this system reveal efficient charge transfer between nanocrystals and the methylene blue dye. Near-infrared photoluminescence measurements provide evidence for an increased efficiency of singlet oxygen production by the methylene blue dye. In vitro studies on the growth of HepG2 and HeLa cancerous cells were also performed, they point toward an improvement in the cell kill efficiency for the methylene blue-semiconductor nanocrystals hybrid system.
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spelling pubmed-28937702010-07-28 CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy Rakovich, Aliaksandra Savateeva, Diana Rakovich, Tatsiana Donegan, John F Rakovich, Yury P Kelly, Vincent Lesnyak, Vladimir Eychmüller, Alexander Nanoscale Res Lett Nano Express We have studied the photodynamic properties of novel CdTe quantum dots—methylene blue hybrid photosensitizer. Absorption spectroscopy, photoluminescence spectroscopy, and fluorescence lifetime imaging of this system reveal efficient charge transfer between nanocrystals and the methylene blue dye. Near-infrared photoluminescence measurements provide evidence for an increased efficiency of singlet oxygen production by the methylene blue dye. In vitro studies on the growth of HepG2 and HeLa cancerous cells were also performed, they point toward an improvement in the cell kill efficiency for the methylene blue-semiconductor nanocrystals hybrid system. Springer 2010-02-10 /pmc/articles/PMC2893770/ /pubmed/20671788 http://dx.doi.org/10.1007/s11671-010-9553-x Text en Copyright © 2010 The Author(s) https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Nano Express
Rakovich, Aliaksandra
Savateeva, Diana
Rakovich, Tatsiana
Donegan, John F
Rakovich, Yury P
Kelly, Vincent
Lesnyak, Vladimir
Eychmüller, Alexander
CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy
title CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy
title_full CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy
title_fullStr CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy
title_full_unstemmed CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy
title_short CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy
title_sort cdte quantum dot/dye hybrid system as photosensitizer for photodynamic therapy
topic Nano Express
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893770/
https://www.ncbi.nlm.nih.gov/pubmed/20671788
http://dx.doi.org/10.1007/s11671-010-9553-x
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