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Drosophila Histone Deacetylase 6 Protects Dopaminergic Neurons against α-Synuclein Toxicity by Promoting Inclusion Formation
Parkinson's disease (PD) is associated with progressive degeneration of dopaminergic (DA) neurons. We report for the first time that the Drosophila histone deacetylase 6 (dHDAC6) plays a critical role in the protection of DA neurons and the formation of α-synuclein inclusions by using a Drosoph...
Autores principales: | Du, Guiping, Liu, Xiang, Chen, Xinping, Song, Mei, Yan, Yan, Jiao, Renjie, Wang, Chih-chen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893978/ https://www.ncbi.nlm.nih.gov/pubmed/20444973 http://dx.doi.org/10.1091/mbc.E10-03-0200 |
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