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TBC-2 Regulates RAB-5/RAB-7-mediated Endosomal Trafficking in Caenorhabditis elegans

During endosome maturation the early endosomal Rab5 GTPase is replaced with the late endosomal Rab7 GTPase. It has been proposed that active Rab5 can recruit and activate Rab7, which in turn could inactivate and remove Rab5. However, many of the Rab5 and Rab7 regulators that mediate endosome maturat...

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Detalles Bibliográficos
Autores principales: Chotard, Laëtitia, Mishra, Ashwini K., Sylvain, Marc-André, Tuck, Simon, Lambright, David G., Rocheleau, Christian E.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893991/
https://www.ncbi.nlm.nih.gov/pubmed/20462958
http://dx.doi.org/10.1091/mbc.E09-11-0947