Cargando…
Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells
Internalization and dynamic subcellular distribution of thiol-capped CdTe quantum dots (QDs) in living cells were studied by means of laser scanning confocal microscopy. These unfunctionalized QDs were well internalized into human hepatocellular carcinoma and rat basophilic leukemia cells in vitro....
Autores principales: | , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893999/ https://www.ncbi.nlm.nih.gov/pubmed/20596411 http://dx.doi.org/10.1007/s11671-009-9307-9 |
_version_ | 1782183113771712512 |
---|---|
author | Zhang, Yu Mi, Lan Xiong, Rongling Wang, Pei-Nan Chen, Ji-Yao Yang, Wuli Wang, Changchun Peng, Qian |
author_facet | Zhang, Yu Mi, Lan Xiong, Rongling Wang, Pei-Nan Chen, Ji-Yao Yang, Wuli Wang, Changchun Peng, Qian |
author_sort | Zhang, Yu |
collection | PubMed |
description | Internalization and dynamic subcellular distribution of thiol-capped CdTe quantum dots (QDs) in living cells were studied by means of laser scanning confocal microscopy. These unfunctionalized QDs were well internalized into human hepatocellular carcinoma and rat basophilic leukemia cells in vitro. Co-localizations of QDs with lysosomes and Golgi complexes were observed, indicating that in addition to the well-known endosome-lysosome endocytosis pathway, the Golgi complex is also a main destination of the endocytosed QDs. The movement of the endocytosed QDs toward the Golgi complex in the perinuclear region of the cell was demonstrated. |
format | Text |
id | pubmed-2893999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Springer |
record_format | MEDLINE/PubMed |
spelling | pubmed-28939992010-06-30 Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells Zhang, Yu Mi, Lan Xiong, Rongling Wang, Pei-Nan Chen, Ji-Yao Yang, Wuli Wang, Changchun Peng, Qian Nanoscale Res Lett Nano Express Internalization and dynamic subcellular distribution of thiol-capped CdTe quantum dots (QDs) in living cells were studied by means of laser scanning confocal microscopy. These unfunctionalized QDs were well internalized into human hepatocellular carcinoma and rat basophilic leukemia cells in vitro. Co-localizations of QDs with lysosomes and Golgi complexes were observed, indicating that in addition to the well-known endosome-lysosome endocytosis pathway, the Golgi complex is also a main destination of the endocytosed QDs. The movement of the endocytosed QDs toward the Golgi complex in the perinuclear region of the cell was demonstrated. Springer 2009-04-05 /pmc/articles/PMC2893999/ /pubmed/20596411 http://dx.doi.org/10.1007/s11671-009-9307-9 Text en Copyright © 2009 to the authors |
spellingShingle | Nano Express Zhang, Yu Mi, Lan Xiong, Rongling Wang, Pei-Nan Chen, Ji-Yao Yang, Wuli Wang, Changchun Peng, Qian Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells |
title | Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells |
title_full | Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells |
title_fullStr | Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells |
title_full_unstemmed | Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells |
title_short | Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells |
title_sort | subcellular localization of thiol-capped cdte quantum dots in living cells |
topic | Nano Express |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893999/ https://www.ncbi.nlm.nih.gov/pubmed/20596411 http://dx.doi.org/10.1007/s11671-009-9307-9 |
work_keys_str_mv | AT zhangyu subcellularlocalizationofthiolcappedcdtequantumdotsinlivingcells AT milan subcellularlocalizationofthiolcappedcdtequantumdotsinlivingcells AT xiongrongling subcellularlocalizationofthiolcappedcdtequantumdotsinlivingcells AT wangpeinan subcellularlocalizationofthiolcappedcdtequantumdotsinlivingcells AT chenjiyao subcellularlocalizationofthiolcappedcdtequantumdotsinlivingcells AT yangwuli subcellularlocalizationofthiolcappedcdtequantumdotsinlivingcells AT wangchangchun subcellularlocalizationofthiolcappedcdtequantumdotsinlivingcells AT pengqian subcellularlocalizationofthiolcappedcdtequantumdotsinlivingcells |