Hyperleptinemia Is Required for the Development of Leptin Resistance

Leptin regulates body weight by signaling to the brain the availability of energy stored as fat. This negative feedback loop becomes disrupted in most obese individuals, resulting in a state known as leptin resistance. The physiological causes of leptin resistance remain poorly understood. Here we t...

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Detalles Bibliográficos
Autores principales: Knight, Zachary A., Hannan, K. Schot, Greenberg, Matthew L., Friedman, Jeffrey M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894068/
https://www.ncbi.nlm.nih.gov/pubmed/20613882
http://dx.doi.org/10.1371/journal.pone.0011376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894068/
https://www.ncbi.nlm.nih.gov/pubmed/20613882
http://dx.doi.org/10.1371/journal.pone.0011376

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