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Impact of Hydrodynamic Injection and phiC31 Integrase on Tumor Latency in a Mouse Model of MYC-Induced Hepatocellular Carcinoma

BACKGROUND: Hydrodynamic injection is an effective method for DNA delivery in mouse liver and is being translated to larger animals for possible clinical use. Similarly, ϕC31 integrase has proven effective in mediating long-term gene therapy in mice when delivered by hydrodynamic injection and is be...

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Detalles Bibliográficos
Autores principales:	Woodard, Lauren E., Keravala, Annahita, Jung, W. Edward, Wapinski, Orly L., Yang, Qiwei, Felsher, Dean W., Calos, Michele P.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894073/ https://www.ncbi.nlm.nih.gov/pubmed/20614008 http://dx.doi.org/10.1371/journal.pone.0011367

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