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Preparation of RGD-modified Long Circulating Liposome Loading Matrine, and its in vitro Anti-cancer Effects

Aim: To prepare RGD-modified long circulating liposome (LCL) loading matrine (RGD-M-LCL) to improve the tumor-targeting and efficacy of matrine. Methods: LCL which was prepared with HSPC, cholesterol, DSPE-PEG2000 and DSPE-PEG-MAL was modified with an RGD motif confirmed by high performance liquid c...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-yan, Ruan, Li-ming, Mao, Wei-wei, Wang, Jin-Qiang, Shen, You-qing, Sui, Mei-hua
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894219/
https://www.ncbi.nlm.nih.gov/pubmed/20596360