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Apoptosis blocks Beclin 1-dependent autophagosome synthesis – an effect rescued by Bcl-xL
Apoptotic cell death is mediated by caspase activation. Autophagy involves the sequestration of cytoplasmic contents into autophagosomes for traffic to lysosomes for degradation. While autophagy is antiapoptotic, increased numbers of autophagosomes have been associated with forms of non-apoptotic ce...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894406/ https://www.ncbi.nlm.nih.gov/pubmed/19713971 http://dx.doi.org/10.1038/cdd.2009.121 |