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Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1

The tumor suppressor protein adenomatous polyposis coli (APC) regulates cell protrusion and cell migration, processes that require the coordinated regulation of actin and microtubule dynamics. APC localizes in vivo to microtubule plus ends and actin-rich cortical protrusions, and has well-documented...

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Detalles Bibliográficos
Autores principales:	Okada, Kyoko, Bartolini, Francesca, Deaconescu, Alexandra M., Moseley, James B., Dogic, Zvonimir, Grigorieff, Nikolaus, Gundersen, Gregg G., Goode, Bruce L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894447/ https://www.ncbi.nlm.nih.gov/pubmed/20566685 http://dx.doi.org/10.1083/jcb.201001016

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