Joining the interface: a site for Nmd3 association on 60S ribosome subunits

The adaptor protein Nmd3 is required for Crm1-dependent export of large ribosomal subunits from the nucleus. In this issue, Sengupta et al. (2010. J. Cell Biol. doi:10.1083/jcb.201001124) identify a binding site for yeast Nmd3 on 60S ribosomal subunits using cryoelectron microscopy and suggest a con...

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Detalles Bibliográficos
Autor principal: Oeffinger, Marlene
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894455/
https://www.ncbi.nlm.nih.gov/pubmed/20584913
http://dx.doi.org/10.1083/jcb.201006033
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author Oeffinger, Marlene
author_facet Oeffinger, Marlene
author_sort Oeffinger, Marlene
collection PubMed
description The adaptor protein Nmd3 is required for Crm1-dependent export of large ribosomal subunits from the nucleus. In this issue, Sengupta et al. (2010. J. Cell Biol. doi:10.1083/jcb.201001124) identify a binding site for yeast Nmd3 on 60S ribosomal subunits using cryoelectron microscopy and suggest a conformational model for its release in the cytoplasm. The study provides the first detailed structural description of a ribosome biogenesis factor in complex with the large subunit.
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spelling pubmed-28944552010-12-28 Joining the interface: a site for Nmd3 association on 60S ribosome subunits Oeffinger, Marlene J Cell Biol Reviews The adaptor protein Nmd3 is required for Crm1-dependent export of large ribosomal subunits from the nucleus. In this issue, Sengupta et al. (2010. J. Cell Biol. doi:10.1083/jcb.201001124) identify a binding site for yeast Nmd3 on 60S ribosomal subunits using cryoelectron microscopy and suggest a conformational model for its release in the cytoplasm. The study provides the first detailed structural description of a ribosome biogenesis factor in complex with the large subunit. The Rockefeller University Press 2010-06-28 /pmc/articles/PMC2894455/ /pubmed/20584913 http://dx.doi.org/10.1083/jcb.201006033 Text en © 2010 Oeffinger This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Oeffinger, Marlene
Joining the interface: a site for Nmd3 association on 60S ribosome subunits
title Joining the interface: a site for Nmd3 association on 60S ribosome subunits
title_full Joining the interface: a site for Nmd3 association on 60S ribosome subunits
title_fullStr Joining the interface: a site for Nmd3 association on 60S ribosome subunits
title_full_unstemmed Joining the interface: a site for Nmd3 association on 60S ribosome subunits
title_short Joining the interface: a site for Nmd3 association on 60S ribosome subunits
title_sort joining the interface: a site for nmd3 association on 60s ribosome subunits
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894455/
https://www.ncbi.nlm.nih.gov/pubmed/20584913
http://dx.doi.org/10.1083/jcb.201006033
work_keys_str_mv AT oeffingermarlene joiningtheinterfaceasitefornmd3associationon60sribosomesubunits

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