Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

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Cell surface receptors integrate chemical and mechanical cues to regulate a wide range of biological processes. Integrin complexes are the mechanotransducers between the extracellular matrix and the actomyosin cytoskeleton. By analogy, cadherin complexes may function as mechanosensors at cell–cell j...

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Detalles Bibliográficos
Autores principales: le Duc, Quint, Shi, Quanming, Blonk, Iris, Sonnenberg, Arnoud, Wang, Ning, Leckband, Deborah, de Rooij, Johan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894457/
https://www.ncbi.nlm.nih.gov/pubmed/20584916
http://dx.doi.org/10.1083/jcb.201001149

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