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Caudal Clonidine in Day-Care Paediatric Surgery
SUMMARY: We evaluated the analgesic efficacy, hemodynamic and respiratory safety of Clonidine when added to bupivacaine for caudal block. Forty children undergoing inguinal hernia repair were randomly given caudal injection with 0.75 ml.kg(−1) of bupivacaine (0.25%) and clonidine 2 μg.kg(−1) in Grou...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Medknow Publications
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894500/ https://www.ncbi.nlm.nih.gov/pubmed/20640207 |
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author | Koul, Archna Pant, Deepanjali Sood, Jayshree |
author_facet | Koul, Archna Pant, Deepanjali Sood, Jayshree |
author_sort | Koul, Archna |
collection | PubMed |
description | SUMMARY: We evaluated the analgesic efficacy, hemodynamic and respiratory safety of Clonidine when added to bupivacaine for caudal block. Forty children undergoing inguinal hernia repair were randomly given caudal injection with 0.75 ml.kg(−1) of bupivacaine (0.25%) and clonidine 2 μg.kg(−1) in Group C or 0.75 ml.kg(−1) of bupivacaine (0.25%) alone in Group B after induction of anaesthesia. Postoperatively duration of analgesia, OPS score (observational pain / discomfort scale), Sedation score, heart rate and blood pressure were recorded. Duration of analgesia was significantly longer (p<0.001) in Group C (10.25 hours) as compared to 4.55 hours in Group B. Bradycardia, hypotension and sedation were not observed in Group C. The addition of Clonidine in caudal blocks prolongs postoperative pain relief in children and is safe alternative to bupivacaine alone in paediatric daycare surgeries. |
format | Text |
id | pubmed-2894500 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-28945002010-07-16 Caudal Clonidine in Day-Care Paediatric Surgery Koul, Archna Pant, Deepanjali Sood, Jayshree Indian J Anaesth Clinical Investigation SUMMARY: We evaluated the analgesic efficacy, hemodynamic and respiratory safety of Clonidine when added to bupivacaine for caudal block. Forty children undergoing inguinal hernia repair were randomly given caudal injection with 0.75 ml.kg(−1) of bupivacaine (0.25%) and clonidine 2 μg.kg(−1) in Group C or 0.75 ml.kg(−1) of bupivacaine (0.25%) alone in Group B after induction of anaesthesia. Postoperatively duration of analgesia, OPS score (observational pain / discomfort scale), Sedation score, heart rate and blood pressure were recorded. Duration of analgesia was significantly longer (p<0.001) in Group C (10.25 hours) as compared to 4.55 hours in Group B. Bradycardia, hypotension and sedation were not observed in Group C. The addition of Clonidine in caudal blocks prolongs postoperative pain relief in children and is safe alternative to bupivacaine alone in paediatric daycare surgeries. Medknow Publications 2009-08 /pmc/articles/PMC2894500/ /pubmed/20640207 Text en © Indian Journal of Anaesthesia http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Investigation Koul, Archna Pant, Deepanjali Sood, Jayshree Caudal Clonidine in Day-Care Paediatric Surgery |
title | Caudal Clonidine in Day-Care Paediatric Surgery |
title_full | Caudal Clonidine in Day-Care Paediatric Surgery |
title_fullStr | Caudal Clonidine in Day-Care Paediatric Surgery |
title_full_unstemmed | Caudal Clonidine in Day-Care Paediatric Surgery |
title_short | Caudal Clonidine in Day-Care Paediatric Surgery |
title_sort | caudal clonidine in day-care paediatric surgery |
topic | Clinical Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894500/ https://www.ncbi.nlm.nih.gov/pubmed/20640207 |
work_keys_str_mv | AT koularchna caudalclonidineindaycarepaediatricsurgery AT pantdeepanjali caudalclonidineindaycarepaediatricsurgery AT soodjayshree caudalclonidineindaycarepaediatricsurgery |