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Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T

Airways secrete considerable amounts of acid. In this study, we investigated the identity and the pH-dependent function of the apical H(+) channel in the airway epithelium. In pH stat recordings of confluent JME airway epithelia in Ussing chambers, Zn-sensitive acid secretion was activated at a muco...

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Detalles Bibliográficos
Autores principales: Iovannisci, David, Illek, Beate, Fischer, Horst
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894549/
https://www.ncbi.nlm.nih.gov/pubmed/20548053
http://dx.doi.org/10.1085/jgp.200910379

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