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Corticosteroid suppression of lipoxin A(4 )and leukotriene B(4)from alveolar macrophages in severe asthma
BACKGROUND: An imbalance in the generation of pro-inflammatory leukotrienes, and counter-regulatory lipoxins is present in severe asthma. We measured leukotriene B(4 )(LTB(4)), and lipoxin A(4 )(LXA(4)) production by alveolar macrophages (AMs) and studied the impact of corticosteroids. METHODS: AMs...
Autores principales: | Bhavsar, Pankaj K, Levy, Bruce D, Hew, Mark J, Pfeffer, Michael A, Kazani, Shamsah, Israel, Elliot, Chung, Kian Fan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894769/ https://www.ncbi.nlm.nih.gov/pubmed/20529300 http://dx.doi.org/10.1186/1465-9921-11-71 |
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