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The CTLA4 variants may interact with the IL23R- and NOD2-conferred risk in development of Crohn's disease

BACKGROUND: The CTLA4 (cytotoxic T-lymphocyte antigen 4) gene is associated with several immunopathologic diseases and because of its important immuno-regulatory role it may be considered also a plausible candidate for a genetic association with inflammatory bowel diseases. Previously published stud...

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Detalles Bibliográficos
Autores principales: Hradsky, Ondrej, Dusatkova, Petra, Lenicek, Martin, Bronsky, Jiri, Nevoral, Jiri, Vitek, Libor, Lukas, Milan, Zeniskova, Ivana, Cinek, Ondrej
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894789/
https://www.ncbi.nlm.nih.gov/pubmed/20537165
http://dx.doi.org/10.1186/1471-2350-11-91

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