Bilateral downregulation of Nav1.8 in dorsal root ganglia of rats with bone cancer pain induced by inoculation with Walker 256 breast tumor cells

BACKGROUND: Rapid and effective treatment of cancer-induced bone pain remains a clinical challenge and patients with bone metastasis are more likely to experience severe pain. The voltage-gated sodium channel Nav1.8 plays a critical role in many aspects of nociceptor function. Therefore, we characte...

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Detalles Bibliográficos
Autores principales: Miao, Xue-Rong, Gao, Xiao-Fei, Wu, Jing-Xiang, Lu, Zhi-Jie, Huang, Zhang-Xiang, Li, Xiao-Qing, He, Cheng, Yu, Wei-Feng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894792/
https://www.ncbi.nlm.nih.gov/pubmed/20482896
http://dx.doi.org/10.1186/1471-2407-10-216

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