Cargando…
Prognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis
BACKGROUND: Most cancers maintain telomeres by activating telomerase but a significant minority, mainly of mesenchymal origin, utilize an alternative lengthening of telomeres (ALT) mechanism. METHODS: In this study we comparatively analyzed the prognostic relevance of ALT in a monoinstitutional seri...
Autores principales: | Venturini, Lorenza, Motta, Rosita, Gronchi, Alessandro, Daidone, MariaGrazia, Zaffaroni, Nadia |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894794/ https://www.ncbi.nlm.nih.gov/pubmed/20525266 http://dx.doi.org/10.1186/1471-2407-10-254 |
Ejemplares similares
-
High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma
por: Cairney, C J, et al.
Publicado: (2008) -
A gene expression signature classifying telomerase and ALT immortalisation reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT
por: Lafferty-Whyte, Kyle, et al.
Publicado: (2009) -
Telomere as a Therapeutic Target in Dedifferentiated Liposarcoma
por: Alessandrini, Irene, et al.
Publicado: (2022) -
Breast Cancer-Initiating Cells: Insights into Novel Treatment Strategies
por: Santilli, Guido, et al.
Publicado: (2011) -
Anti-Tumor Effect of Apatinib and Relevant Mechanisms in Liposarcoma
por: Cui, Lixuan, et al.
Publicado: (2021)