Animal Ca(2+ )release-activated Ca(2+ )(CRAC) channels appear to be homologous to and derived from the ubiquitous cation diffusion facilitators

BACKGROUND: Antigen stimulation of immune cells triggers Ca(2+ )entry through Ca(2+ )release-activated Ca(2+ )(CRAC) channels, promoting an immune response to pathogens. Defects in a CRAC (Orai) channel in humans gives rise to the hereditary Severe Combined Immune Deficiency (SCID) syndrome. We here...

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Detalles Bibliográficos
Autores principales: Matias, Madeleine G, Gomolplitinant, Kenny M, Tamang, Dorjee G, Saier, Milton H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894845/
https://www.ncbi.nlm.nih.gov/pubmed/20525303
http://dx.doi.org/10.1186/1756-0500-3-158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894845/
https://www.ncbi.nlm.nih.gov/pubmed/20525303
http://dx.doi.org/10.1186/1756-0500-3-158

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