RB1CC1 Activates RB1 Pathway and Inhibits Proliferation and Cologenic Survival in Human Cancer

RB1-inducible coiled-coil 1 (RB1CC1, also known as FIP200) plays a role in the enhancement of the RB1 pathway through the direct binding to a GC-rich region 201bp upstream (from the initiation ATG) of the RB1 promoter. Here, we identified hSNF5 and p53 as the binding partners of RB1CC1 by immunoprec...

Descripción completa

Detalles Bibliográficos
Autores principales: Chano, Tokuhiro, Ikebuchi, Kaichiro, Ochi, Yasuko, Tameno, Hitosuke, Tomita, Yasuhiko, Jin, Yufen, Inaji, Hideo, Ishitobi, Makoto, Teramoto, Koji, Nishimura, Ichiro, Minami, Kahori, Inoue, Hirokazu, Isono, Takahiro, Saitoh, Masao, Shimada, Taketoshi, Hisa, Yasuo, Okabe, Hidetoshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894861/
https://www.ncbi.nlm.nih.gov/pubmed/20614030
http://dx.doi.org/10.1371/journal.pone.0011404

Ejemplares similares

Ejemplares similares