Presence of two alternative kdr-like mutations, L1014F and L1014S, and a novel mutation, V1010L, in the voltage gated Na(+ )channel of Anopheles culicifacies from Orissa, India

BACKGROUND: Knockdown resistance in insects resulting from mutation(s) in the voltage gated Na(+ )channel (VGSC) is one of the mechanisms of resistance against DDT and pyrethroids. Recently a point mutation leading to Leu-to-Phe substitution in the VGSC at residue 1014, a most common kdr mutation in...

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Detalles Bibliográficos
Autores principales: Singh, Om P, Dykes, Cherry L, Das, Manoj K, Pradhan, Sabyasachi, Bhatt, Rajendra M, Agrawal, Om P, Adak, Tridibes
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895608/
https://www.ncbi.nlm.nih.gov/pubmed/20509922
http://dx.doi.org/10.1186/1475-2875-9-146

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