Genetic Variation in Cholinergic-Muscarinic-2 Receptor Gene Modulates Muscarinic(2)-Receptor Binding In Vivo and Accounts for Reduced Binding in Bipolar Disorder

Genetic variation in the cholinergic-muscarinic2 (M(2))receptor gene (CHRM2) has been associated with the risk for developing depression. We previously reported that M(2)-receptor distribution volume (V(T)) was reduced in depressed subjects with bipolar disorder (BD) relative to depressed subjects w...

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Detalles Bibliográficos
Autores principales: Cannon, DM, Klaver, JK, Gandhi, SK, Solorio, G, Peck, SA, Erickson, K, Savitz, J, Akula, N, Eckelman, WC, Furey, ML, Sahakian, BJ, McMahon, FJ, Drevets, WC
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895691/
https://www.ncbi.nlm.nih.gov/pubmed/20351719
http://dx.doi.org/10.1038/mp.2010.24

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