Protein annotation and modelling servers at University College London

The UCL Bioinformatics Group web portal offers several high quality protein structure prediction and function annotation algorithms including PSIPRED, pGenTHREADER, pDomTHREADER, MEMSAT, MetSite, DISOPRED2, DomPred and FFPred for the prediction of secondary structure, protein fold, protein structura...

Descripción completa

Detalles Bibliográficos
Autores principales: Buchan, D. W. A., Ward, S. M., Lobley, A. E., Nugent, T. C. O., Bryson, K., Jones, D. T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896093/
https://www.ncbi.nlm.nih.gov/pubmed/20507913
http://dx.doi.org/10.1093/nar/gkq427
_version_ 1782183308163022848
author Buchan, D. W. A.
Ward, S. M.
Lobley, A. E.
Nugent, T. C. O.
Bryson, K.
Jones, D. T.
author_facet Buchan, D. W. A.
Ward, S. M.
Lobley, A. E.
Nugent, T. C. O.
Bryson, K.
Jones, D. T.
author_sort Buchan, D. W. A.
collection PubMed
description The UCL Bioinformatics Group web portal offers several high quality protein structure prediction and function annotation algorithms including PSIPRED, pGenTHREADER, pDomTHREADER, MEMSAT, MetSite, DISOPRED2, DomPred and FFPred for the prediction of secondary structure, protein fold, protein structural domain, transmembrane helix topology, metal binding sites, regions of protein disorder, protein domain boundaries and protein function, respectively. We also now offer a fully automated 3D modelling pipeline: BioSerf, which performed well in CASP8 and uses a fragment-assembly approach which placed it in the top five servers in the de novo modelling category. The servers are available via the group web site at http://bioinf.cs.ucl.ac.uk/.
format Text
id pubmed-2896093
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-28960932010-07-02 Protein annotation and modelling servers at University College London Buchan, D. W. A. Ward, S. M. Lobley, A. E. Nugent, T. C. O. Bryson, K. Jones, D. T. Nucleic Acids Res Articles The UCL Bioinformatics Group web portal offers several high quality protein structure prediction and function annotation algorithms including PSIPRED, pGenTHREADER, pDomTHREADER, MEMSAT, MetSite, DISOPRED2, DomPred and FFPred for the prediction of secondary structure, protein fold, protein structural domain, transmembrane helix topology, metal binding sites, regions of protein disorder, protein domain boundaries and protein function, respectively. We also now offer a fully automated 3D modelling pipeline: BioSerf, which performed well in CASP8 and uses a fragment-assembly approach which placed it in the top five servers in the de novo modelling category. The servers are available via the group web site at http://bioinf.cs.ucl.ac.uk/. Oxford University Press 2010-07-01 2010-05-27 /pmc/articles/PMC2896093/ /pubmed/20507913 http://dx.doi.org/10.1093/nar/gkq427 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Buchan, D. W. A.
Ward, S. M.
Lobley, A. E.
Nugent, T. C. O.
Bryson, K.
Jones, D. T.
Protein annotation and modelling servers at University College London
title Protein annotation and modelling servers at University College London
title_full Protein annotation and modelling servers at University College London
title_fullStr Protein annotation and modelling servers at University College London
title_full_unstemmed Protein annotation and modelling servers at University College London
title_short Protein annotation and modelling servers at University College London
title_sort protein annotation and modelling servers at university college london
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896093/
https://www.ncbi.nlm.nih.gov/pubmed/20507913
http://dx.doi.org/10.1093/nar/gkq427
work_keys_str_mv AT buchandwa proteinannotationandmodellingserversatuniversitycollegelondon
AT wardsm proteinannotationandmodellingserversatuniversitycollegelondon
AT lobleyae proteinannotationandmodellingserversatuniversitycollegelondon
AT nugenttco proteinannotationandmodellingserversatuniversitycollegelondon
AT brysonk proteinannotationandmodellingserversatuniversitycollegelondon
AT jonesdt proteinannotationandmodellingserversatuniversitycollegelondon

Ejemplares similares