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HotPoint: hot spot prediction server for protein interfaces
The energy distribution along the protein–protein interface is not homogenous; certain residues contribute more to the binding free energy, called ‘hot spots’. Here, we present a web server, HotPoint, which predicts hot spots in protein interfaces using an empirical model. The empirical model incorp...
Autores principales: | Tuncbag, Nurcan, Keskin, Ozlem, Gursoy, Attila |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896123/ https://www.ncbi.nlm.nih.gov/pubmed/20444871 http://dx.doi.org/10.1093/nar/gkq323 |
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