DIALIGN-TX and multiple protein alignment using secondary structure information at GOBICS

We introduce web interfaces for two recent extensions of the multiple-alignment program DIALIGN. DIALIGN-TX combines the greedy heuristic previously used in DIALIGN with a more traditional ‘progressive’ approach for improved performance on locally and globally related sequence sets. In addition, we...

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Detalles Bibliográficos
Autores principales: Subramanian, Amarendran R., Hiran, Suvrat, Steinkamp, Rasmus, Meinicke, Peter, Corel, Eduardo, Morgenstern, Burkhard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896137/
https://www.ncbi.nlm.nih.gov/pubmed/20497995
http://dx.doi.org/10.1093/nar/gkq442
Descripción
Sumario:We introduce web interfaces for two recent extensions of the multiple-alignment program DIALIGN. DIALIGN-TX combines the greedy heuristic previously used in DIALIGN with a more traditional ‘progressive’ approach for improved performance on locally and globally related sequence sets. In addition, we offer a version of DIALIGN that uses predicted protein secondary structures together with primary sequence information to construct multiple protein alignments. Both programs are available through ‘Göttingen Bioinformatics Compute Server’ (GOBICS).

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