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ANCHOR: a web server and database for analysis of protein–protein interaction binding pockets for drug discovery

ANCHOR is a web-based tool whose aim is to facilitate the analysis of protein–protein interfaces with regard to its suitability for small molecule drug design. To this end, ANCHOR exploits the so-called anchor residues, i.e. amino acid side-chains deeply buried at protein–protein interfaces, to indi...

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Detalles Bibliográficos
Autores principales: Meireles, Lidio M. C., Dömling, Alexander S., Camacho, Carlos J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896143/
https://www.ncbi.nlm.nih.gov/pubmed/20525787
http://dx.doi.org/10.1093/nar/gkq502