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Multi-Harmony: detecting functional specificity from sequence alignment
Many protein families contain sub-families with functional specialization, such as binding different ligands or being involved in different protein–protein interactions. A small number of amino acids generally determine functional specificity. The identification of these residues can aid the underst...
Autores principales: | Brandt, Bernd W., Feenstra, K. Anton, Heringa, Jaap |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896201/ https://www.ncbi.nlm.nih.gov/pubmed/20525785 http://dx.doi.org/10.1093/nar/gkq415 |
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