Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature

This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal carcinoma in situ with positive TTF-1 is a strong indication that this is a primary tumour and not a metastasis fr...

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Detalles Bibliográficos
Autores principales: Klingen, Tor A, Chen, Ying, Gundersen, Marian D, Aas, Hans, Westre, Bjørn, Sauer, Torill
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896353/
https://www.ncbi.nlm.nih.gov/pubmed/20565809
http://dx.doi.org/10.1186/1746-1596-5-37
Descripción
Sumario:This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal carcinoma in situ with positive TTF-1 is a strong indication that this is a primary tumour and not a metastasis from lung. On PET scan and CT follow up there were no other tumours found in this patient. We are not aware of any previously reported TTF-1 positive primary breast carcinoma with ductal differentiation.

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