Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature

This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal carcinoma in situ with positive TTF-1 is a strong indication that this is a primary tumour and not a metastasis fr...

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Autores principales: Klingen, Tor A, Chen, Ying, Gundersen, Marian D, Aas, Hans, Westre, Bjørn, Sauer, Torill
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896353/
https://www.ncbi.nlm.nih.gov/pubmed/20565809
http://dx.doi.org/10.1186/1746-1596-5-37
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author Klingen, Tor A
Chen, Ying
Gundersen, Marian D
Aas, Hans
Westre, Bjørn
Sauer, Torill
author_facet Klingen, Tor A
Chen, Ying
Gundersen, Marian D
Aas, Hans
Westre, Bjørn
Sauer, Torill
author_sort Klingen, Tor A
collection PubMed
description This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal carcinoma in situ with positive TTF-1 is a strong indication that this is a primary tumour and not a metastasis from lung. On PET scan and CT follow up there were no other tumours found in this patient. We are not aware of any previously reported TTF-1 positive primary breast carcinoma with ductal differentiation.
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spelling pubmed-28963532010-07-03 Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature Klingen, Tor A Chen, Ying Gundersen, Marian D Aas, Hans Westre, Bjørn Sauer, Torill Diagn Pathol Case Report This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal carcinoma in situ with positive TTF-1 is a strong indication that this is a primary tumour and not a metastasis from lung. On PET scan and CT follow up there were no other tumours found in this patient. We are not aware of any previously reported TTF-1 positive primary breast carcinoma with ductal differentiation. BioMed Central 2010-06-17 /pmc/articles/PMC2896353/ /pubmed/20565809 http://dx.doi.org/10.1186/1746-1596-5-37 Text en Copyright ©2010 Klingen et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Klingen, Tor A
Chen, Ying
Gundersen, Marian D
Aas, Hans
Westre, Bjørn
Sauer, Torill
Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
title Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
title_full Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
title_fullStr Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
title_full_unstemmed Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
title_short Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
title_sort thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896353/
https://www.ncbi.nlm.nih.gov/pubmed/20565809
http://dx.doi.org/10.1186/1746-1596-5-37
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