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Inferring predominant pathways in cellular models of breast cancer using limited sample proteomic profiling

BACKGROUND: Molecularly targeted drugs inhibit aberrant signaling within oncogenic pathways. Identifying the predominant pathways at work within a tumor is a key step towards tailoring therapies to the patient. Clinical samples pose significant challenges for proteomic profiling, an attractive appro...

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Detalles Bibliográficos
Autores principales: Kulkarni, Yogesh M, Suarez, Vivian, Klinke, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896362/
https://www.ncbi.nlm.nih.gov/pubmed/20550684
http://dx.doi.org/10.1186/1471-2407-10-291