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Inferring predominant pathways in cellular models of breast cancer using limited sample proteomic profiling
BACKGROUND: Molecularly targeted drugs inhibit aberrant signaling within oncogenic pathways. Identifying the predominant pathways at work within a tumor is a key step towards tailoring therapies to the patient. Clinical samples pose significant challenges for proteomic profiling, an attractive appro...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896362/ https://www.ncbi.nlm.nih.gov/pubmed/20550684 http://dx.doi.org/10.1186/1471-2407-10-291 |