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Beta(1)-Adrenoceptor Polymorphism Predicts Flecainide Action in Patients with Atrial Fibrillation
BACKGROUND: Antiarrhythmic action of flecainide is based on sodium channel blockade. Beta(1)-adrenoceptor (β(1)AR) activation induces sodium channel inhibition, too. The aim of the present study was to evaluate the impact of different β(1)AR genotypes on antiarrhythmic action of flecainide in patien...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896398/ https://www.ncbi.nlm.nih.gov/pubmed/20625396 http://dx.doi.org/10.1371/journal.pone.0011421 |