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Beta(1)-Adrenoceptor Polymorphism Predicts Flecainide Action in Patients with Atrial Fibrillation

BACKGROUND: Antiarrhythmic action of flecainide is based on sodium channel blockade. Beta(1)-adrenoceptor (β(1)AR) activation induces sodium channel inhibition, too. The aim of the present study was to evaluate the impact of different β(1)AR genotypes on antiarrhythmic action of flecainide in patien...

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Detalles Bibliográficos
Autores principales:	Nia, Amir M., Caglayan, Evren, Gassanov, Natig, Zimmermann, Tom, Aslan, Orhan, Hellmich, Martin, Duru, Firat, Erdmann, Erland, Rosenkranz, Stephan, Er, Fikret
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896398/ https://www.ncbi.nlm.nih.gov/pubmed/20625396 http://dx.doi.org/10.1371/journal.pone.0011421

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