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γδ T Cells Are Reduced and Rendered Unresponsive by Hyperglycemia and Chronic TNFα in Mouse Models of Obesity and Metabolic Disease
Epithelial cells provide an initial line of defense against damage and pathogens in barrier tissues such as the skin; however this balance is disrupted in obesity and metabolic disease. Skin γδ T cells recognize epithelial damage, and release cytokines and growth factors that facilitate wound repair...
Autores principales: | Taylor, Kristen R., Mills, Robyn E., Costanzo, Anne E., Jameson, Julie M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896399/ https://www.ncbi.nlm.nih.gov/pubmed/20625397 http://dx.doi.org/10.1371/journal.pone.0011422 |
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