Cargando…
A TRANSCRIPTIONAL CROSS–TALK BETWEEN RhoA AND c–Myc INHIBITS THE RhoA/Rock–DEPENDENT CYTOSKELETON
The GTPase RhoA participates in a number of cellular processes, including cytoskeletal organization, mitogenesis and tumorigenesis. We have previously shown that the transforming activity of an oncogenic version of RhoA (Q63L mutant) was highly dependent on the transcriptional factor c–Myc. In contr...
Autores principales: | Sauzeau, Vincent, Berenjeno, Inmaculada M., Citterio, Carmen, Bustelo, Xosé R. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896432/ https://www.ncbi.nlm.nih.gov/pubmed/20453885 http://dx.doi.org/10.1038/onc.2010.134 |
Ejemplares similares
-
Leptin Activates RhoA/ROCK Pathway to Induce Cytoskeleton Remodeling in Nucleus Pulposus Cells
por: Li, Zheng, et al.
Publicado: (2014) -
RhoA Regulates Peroxisome Association to Microtubules and the Actin Cytoskeleton
por: Schollenberger, Lukas, et al.
Publicado: (2010) -
RhoA and RhoC Are Both Required for the ROCK II-Dependent Promotion of Centrosome Duplication
por: Kanai, Masayuki, et al.
Publicado: (2010) -
Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
por: Zhang, Jason Z., et al.
Publicado: (2020) -
The RhoA-ROCK pathway in the regulation of T and B cell responses
por: Ricker, Edd, et al.
Publicado: (2016)