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Torsional regulation of hRPA-induced unwinding of double-stranded DNA

All cellular single-stranded (ss) DNA is rapidly bound and stabilized by single stranded DNA-binding proteins (SSBs). Replication protein A, the main eukaryotic SSB, is able to unwind double-stranded (ds) DNA by binding and stabilizing transiently forming bubbles of ssDNA. Here, we study the dynamic...

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Detalles Bibliográficos
Autores principales:	De Vlaminck, Iwijn, Vidic, Iztok, van Loenhout, Marijn T. J., Kanaar, Roland, Lebbink, Joyce H. G., Dekker, Cees
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896508/ https://www.ncbi.nlm.nih.gov/pubmed/20197317 http://dx.doi.org/10.1093/nar/gkq067

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