Identification of a structural element of the hepatitis C virus minus strand RNA involved in the initiation of RNA synthesis

The replication of the genomic RNA of the hepatitis C virus (HCV) of positive polarity involves the synthesis of a replication intermediate of negative polarity by the viral RNA-dependent RNA polymerase (NS5B). In vitro and likely in vivo, the NS5B initiates RNA synthesis without primers. This de no...

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Detalles Bibliográficos
Autores principales: Mahias, Kathleen, Ahmed-El-Sayed, Neveen, Masante, Cyril, Bitard, Juliette, Staedel, Cathy, Darfeuille, Fabien, Ventura, Michel, Astier-Gin, Thérèse
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896513/
https://www.ncbi.nlm.nih.gov/pubmed/20194114
http://dx.doi.org/10.1093/nar/gkq109

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