Synchronization in G(0)/G(1) enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin

Evaluating mitogenic signaling specifically through the human insulin receptor (IR) is relevant for the preclinical safety assessment of developmental insulin analogs. It is known that overexpression of IR sensitizes cells to the mitogenic effects of insulin, but it is essentially unknown how mitoge...

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Detalles Bibliográficos
Autores principales: Bonnesen, Christine, Nelander, Gitte-Mai, Hansen, Bo Falck, Jensen, Pia, Krabbe, Jonas S., Jensen, Marianne B., Hegelund, Anne Charlotte, Svendsen, Jette E., Oleksiewicz, Martin B.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896650/
https://www.ncbi.nlm.nih.gov/pubmed/19898946
http://dx.doi.org/10.1007/s10565-009-9142-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896650/
https://www.ncbi.nlm.nih.gov/pubmed/19898946
http://dx.doi.org/10.1007/s10565-009-9142-x

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