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Synchronization in G(0)/G(1) enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin
Evaluating mitogenic signaling specifically through the human insulin receptor (IR) is relevant for the preclinical safety assessment of developmental insulin analogs. It is known that overexpression of IR sensitizes cells to the mitogenic effects of insulin, but it is essentially unknown how mitoge...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896650/ https://www.ncbi.nlm.nih.gov/pubmed/19898946 http://dx.doi.org/10.1007/s10565-009-9142-x |