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Development of Th1 Imprints to rBCG Expressing a Foreign Protein: Implications for Vaccination against HIV-1 and Diverse Influenza Strains

We demonstrate here that immunizing naïve mice with low numbers of recombinant Bacille Calmette-Guérin (rBCG) expressing β-galactosidase (β-gal) generates predominant Th1 responses to both BCG and β-gal whereas infection with high numbers generates a mixed Th1/Th2 response to both BCG and β-gal. Fur...

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Detalles Bibliográficos
Autores principales:	Power, Carl, Marfleet, Travis W., Qualtiere, Louis, Xiao, Wei, Bretscher, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896700/ https://www.ncbi.nlm.nih.gov/pubmed/20625498 http://dx.doi.org/10.1155/2010/591348

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